Rabbit anti-HMGN1 IHC Antibody Affinity Purified
Catalog #
HMGN1
Human
,Mouse
IHC
,IHC-IF
Rabbit
Polyclonal
Whole IgG
Between 90 and 100
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Horse,
Dog,
Pig,
Monkey
Human
2 - 8 °C
1 year from date of receipt
Antibody was affinity purified using an epitope specific to HMGN1 immobilized on solid support.
The epitope recognized by IHC-00670 maps to a region between residue 90 and 100 of human high-mobility group nucleosome binding domain 1 using the numbering given in entry NP_004956.5 (GeneID 3150).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to HMGN1 immobilized on solid support.
The epitope recognized by IHC-00670-T maps to a region between residue 90 and 100 of human high-mobility group nucleosome binding domain 1 using the numbering given in entry NP_004956.5 (GeneID 3150).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
HMGN1 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA to potentially alter the interaction between the DNA and the histone octamer. The two proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function [taken from NCBI Entrez Gene (GeneID:3150)].
Non-histone chromosomal protein HMG-14
Alternate Names
high mobility group nucleosome-binding domain-containing protein 1; high-mobility group (nonhistone chromosomal) protein 14; high-mobility group nucleosome binding 1; HMG14; non-histone chromosomal protein HMG-14; nonhistone chromosomal protein HMG-14
Applications
