Rabbit anti-FUSIP1 IHC Antibody Affinity Purified
Catalog #
FUSIP1
Human
IHC
,IHC-IF
Rabbit
Polyclonal
Whole IgG
Between 133 and 183
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Pig,
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
Antibody was affinity purified using an epitope specific to FUSIP1 immobilized on solid support.
The epitope recognized by IHC-00642 maps to a region between residue 133 and 183 of human FUS interacting protein (serine/arginine-rich) 1 using the numbering given in entry NP_006616.1 (GeneID 10772).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to FUSIP1 immobilized on solid support.
The epitope recognized by IHC-00642-T maps to a region between residue 133 and 183 of human FUS interacting protein (serine/arginine-rich) 1 using the numbering given in entry NP_006616.1 (GeneID 10772).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
FUSIP1 (FUS-interacting protein 1) was originally identified in a two-hybrid screen for partners of the TLS (translocated in liposarcoma) protein also known as FUS. FUSIP1 is a splicing factor of the serine-arginine (SR) family of proteins. It functions as a splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. FUSIP1 seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70, and it is required for splicing repression in M-phase cells and after heat shock [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75494].
Serine/arginine-rich splicing factor 10
Alternate Names
40 kDa SR-repressor protein; FUS-interacting protein (serine-arginine rich) 2; FUS-interacting serine-arginine-rich protein 1; FUSIP1; FUSIP2; neural-salient SR protein; NSSR; PPP1R149; protein phosphatase 1, regulatory subunit 149; serine/arginine-rich splicing factor 10; serine-arginine repressor protein (40 kDa); SFRS13; SFRS13A; splicing factor SRp38; splicing factor, arginine/serine-rich 13; splicing factor, arginine/serine-rich 13A; SR splicing factor 10; SRp38; SRrp40; TASR; TASR1; TASR2; TLS-associated protein TASR; TLS-associated protein with Ser-Arg repeats; TLS-associated protein with SR repeats; TLS-associated serine-arginine protein
Applications
