Rabbit anti-FOXO4 Antibody Affinity Purified
Catalog #
FOXO4
Human
WB
Rabbit
Polyclonal
Whole IgG
between 455 and 505
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
FOXO4 (fork-head box O4) is a fork-head DNA-binding domain containing protein and functions as a transcription factor involved in the regulation of the insulin signaling pathway. FOXO4 binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. It also down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes, and is involved in the negative regulation of the cell cycle [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P98177].
Alternate Names
AFX; AFX1; fork head domain transcription factor AFX1; forkhead box protein O4; MLLT7; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7
Applications