Rabbit anti-Filamin A IHC Antibody Affinity Purified
Catalog #
Filamin A
Human
IHC
,IHC-IF
Rabbit
Polyclonal
Whole IgG
Between 1725 and 1775
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Monkey
Human
2 - 8 °C
1 year from date of receipt
Antibody was affinity purified using an epitope specific to Filamin A immobilized on solid support.
The epitope recognized by IHC-00225 maps to a region between residue 1725 and 1775 of human Filamin A using the numbering given in entry NP_001447.1 (GeneID 2316).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to Filamin A immobilized on solid support.
The epitope recognized by IHC-00225-T maps to a region between residue 1725 and 1775 of human Filamin A using the numbering given in entry NP_001447.1 (GeneID 2316).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Filamin A is an actin-binding protein that crosslinks and promotes orthogonal branching of actin filaments and also functions to anchor transmembrane proteins and intracellular signaling proteins to the actin cytoskeleton. As a scaffolding protein, filamin A is able to act as a link between cell membrane receptors and intracellular signaling proteins. Defects in filamin A are associated with multiple human diseases characterized by abnormalities in bone and neurological development.
Alternate Names
ABP-280; ABPX; actin binding protein 280; Actin-binding protein 280; alpha-filamin; CSBS; CVD1; endothelial actin-binding protein; epididymis secretory sperm binding protein; FGS2; filamin A, alpha; filamin-1; filamin-A; FLN; FLN1; FLN-A; FMD; MNS; NHBP; non-muscle filamin; OPD; OPD1; OPD2; XLVD; XMVD
Applications