NEW!
Rabbit anti-FASN IHC Antibody Affinity Purified
Bethyl Laboratories
Catalog #
Validated
Target:
FASN
Reactivity:
Human
,Mouse
Applications:
IHC
,IHC-IF
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 2462 and 2511
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)
10 µl (5+ slides)
Product Details
Specifications
Verified Reactivity
Mouse,
Human
Presumed Reactivity
Guinea Pig,
Horse,
Goat,
Zebra Finch,
Dog,
Rabbit,
Bovine,
Monkey,
Rat
Antigen Species
Human
Concentration
250 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Production Procedures
Antibody was affinity purified using an epitope specific to FASN immobilized on solid support.
The epitope recognized by IHC-00305 maps to a region between residue 2462 and 2511 of human fatty acid synthase using the numbering given in entry NP_004095.4 (GeneID 2194).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to FASN immobilized on solid support.
The epitope recognized by IHC-00305-T maps to a region between residue 2462 and 2511 of human fatty acid synthase using the numbering given in entry NP_004095.4 (GeneID 2194).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
Fatty acid synthase (FASN) is a multifunctional protein that is mainly involved in catalyzing the synthesis of long-chain fatty acids. FASN has recently been viewed as an important protein involved in carcinogenesis as it has been found to be constitutively active in subsets of carcinomas and is associated with a poor prognosis. The inhibition of FASN activity in cancer cells promotes apoptosis and thus may play a role in maintaining cancer cell survival.
Alternate Names
Acyl-carrier-protein S-acetyltransferase; Acyl-carrier-protein S-malonyltransferase; 3-hydroxyacyl-acyl-carrier-protein dehydratase; 3-oxoacyl-acyl-carrier-protein reductase; Enoyl-acyl-carrier-protein reductase; FAS; fatty acid synthase; OA-519; Oleoyl-acyl-carrier-protein hydrolase; SDR27X1; short chain dehydrogenase/reductase family 27X, member 1
Applications
