/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-FANCB Antibody
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Primary Antibodies  

Rabbit anti-FANCB Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

FANCB

Reactivity:

Human

Applications:

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 820 and 859

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

FANCB (Fanconi anemia complementation group B) is part of a DNA repair network which involves BRCA1 and BRCA2 and required for the ubiquitination of FANCD2. The FANCB gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. The FANC members are not homologous proteins but are related by their assembly into a common nuclear complex. Defects in FANCB are the cause of Fanconi pancytopenia type 2, Fanconi anemia, and X-linked VACTERL.

2187

FANCB

FA complementation group B

Q8NB91

Fanconi anemia group B protein

Alternate Names

FA2; FAAP90; FAAP95; FAB; FACB; Fanconi anemia complementation group B; Fanconi anemia group B protein; Fanconi anemia-associated polypeptide of 95 kDa; Protein FACB

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.