/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-EphA2 Recombinant Monoclonal Antibody [BLR136H]
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Primary Antibodies  

Rabbit anti-EphA2 Recombinant Monoclonal Antibody [BLR136H]

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

EphA2

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR136H

Format:

Whole IgG

Immunogen:

residues 25-534 (ECD)

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (10 blots)

20 µl (2 blots)

100 µg (BSA-Free)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
40 µg/ml 1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide


Request Formulation Change

Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free


Request Formulation Change
Additional Product Information

Ephrin type-A receptor 2 (EphA2) is a member of the Eph family of tyrosine kinase receptors. Eph receptors have been shown to play a critical role in the development of the nervous system, where they regulate patterning during neural development. The ligands for Eph receptors are ephrins. Ephrin receptors and ligands have been found to be frequently overexpressed in a wide variety of cancers. Contrary to the usual finding that the oncogenic properties of tyrosine kinase receptors are promoted by the autophosphorylation of the receptor, it is the dephosphorylation of EphA2 that is associated with its oncogenic activity. The major study of EphA2 has been in relation to its contribution to malignancy and the possibility of targeting it in cancer therapy.

1969

EPHA2

EPH receptor A2

P29317

Ephrin type-A receptor 2

Alternate Names

ARCC2; CTPA; CTPP1; CTRCT6; ECK; ephrin type-A receptor 2; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.