Rabbit anti-DKC1 Antibody Affinity Purified
Catalog #
DKC1
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 340 and 390
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Chicken,
Rat,
D. melanogaster
Human
2 - 8 °C
1 year from date of receipt
Dyskeratosis congenita 1(DKC1) is also known as dyskerin. DKC1 is required for ribosome biogenesis and telomere maintenance. It is a probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. DKC1 is also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. Defects in DKC1 are a cause of dyskeratosis congenita X-linked recessive (XDKC), a rare progressive bone marrow failure syndrome [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O60832].
Alternate Names
CBF5; CBF5 homolog; DKC; DKCX; dyskeratosis congenita 1, dyskerin; Dyskerin; H/ACA ribonucleoprotein complex subunit 4; H/ACA ribonucleoprotein complex subunit DKC1; NAP57; NOLA4; nopp140-associated protein of 57 kDa; nucleolar protein family A member 4; nucleolar protein NAP57; snoRNP protein DKC1; XAP101
Applications