/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-CIZ Antibody
Primary Antibodies  

Rabbit anti-CIZ Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

CIZ

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 527 and C-terminus

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Rat

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

CAS-interacting zinc finger protein (CIZ) is also known as nuclear matrix protein 4 (NMP4) and the gene name zinc finger protein 384 (ZNF384). CIZ is a C2H2-type zinc finger protein, which may function as a transcription factor. CIZ appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling [taken from NCBI Entrez Gene (Gene ID: 171017)].

171017

ZNF384

zinc finger protein 384

Q8TF68

Zinc finger protein 384

Alternate Names

CAG repeat protein 1; CAGH1; CAGH1A; Cas-interacting zinc finger protein; CI; ZERDA2; expanded repeat domain, CAG/CTG 2; NMP4; NP; Nuclear matrix protein 4; nuclear matrix transcription factor 4; TNRC1; trinucleotide repeat-containing gene 1 protein; zinc finger protein 384

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.