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Rabbit anti-CDK5RAP2 IHC Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

CDK5RAP2

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 1843 and C-term

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
250 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Production Procedures

Antibody was affinity purified using an epitope specific to CDK5RAP2 immobilized on solid support.

The epitope recognized by IHC-00063 maps to a region between residues 1843 and the C-terminus (residue 1893) of human CDK5 Regulatory Subunit Associated Protein 2 using the numbering given in entry NP_060719.4 (GeneID 55755).

Antibody was affinity purified using an epitope specific to CDK5RAP2 immobilized on solid support.

The epitope recognized by IHC-00063-T maps to a region between residues 1843 and the C-terminus (residue 1893) of human CDK5 Regulatory Subunit Associated Protein 2 using the numbering given in entry NP_060719.4 (GeneID 55755).

Additional Product Information

Mutations in CDK5RAP2 (CDK5 regulatory subunit-associated protein 2) have been linked to microcephaly. CDK5RAP2 may be involved in centrosome directed production of microtubules and mitotic spindle formation during neural cell division. CDK5RAP2 associates with the activating subunit of Cdk5, p25NCK5A. Cdk5 is a brain specific cyclin-dependent kinase important to mammalian brain development.

55755

CDK5RAP2

CDK5 regulatory subunit associated protein 2

Q96SN8

CDK5 regulatory subunit-associated protein 2

Alternate Names

C48; CDK5 activator-binding protein C48; CDK5 regulatory subunit-associated protein 2; centrosomal protein 215 kDa; Centrosome-associated protein 215; centrosomin; Cep215; MCPH3

Applications

Formaldehyde-Fixed Cells 1:100 - 1:500:

Permeabilization with Triton-X 100 is recommended.

Methanol-Fixed Cells: 1:100 - 1:500:

Acetone fixation is not recommended.