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Rabbit anti-BRD3 IHC Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

BRD3

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 676 and 726

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Monkey

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

BRD3 (bromodomain containing 3) is a double bromo-domain containing protein. It has been shown to associate with hyperacetylated chromatin of transcribed genes. From this finding it is suggested that BRD3 plays a role in RNA polymerase II transcription through nucleosomes. A chromosomal translocation resulting in a fusion protein involving BRD3 and NUT has been associated with a rare and lethal carcinoma. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15059 and from NCBI Entrez Gene (Gene ID: 8019)].

8019

BRD3

bromodomain containing 3

Q15059

Bromodomain-containing protein 3

Alternate Names

bromodomain-containing protein 3; bromodomain-containing protein 3 short isoform; ORFX; RING3L; RING3-like protein

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.