Rabbit anti-BCoR Antibody
Catalog #
BCoR
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 1705 and 1755
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
The BCL6 co-repressor (BCOR) was identified in a two-hybrid screen for factors that interact with the POZ domain of BCL6, a transcriptional repressor important to the immune response and B-cell development. BCOR also interacts with class I and II histone deacetylases and has recently been identified in a complexes with polycomb group proteins, RING1, RYBP, SNSC1, and RNF2, and the ubiquitin E3 ligase SKP1, and JHDM1B. Defects in BCOR are associated with oculo-facio-cardio-dental (OFCD) syndrome, a rare X-linked dominant disease that is fatal in males.
Alternate Names
ANOP2; BCL-6 corepressor; BCL-6 interacting corepressor; BCoR; MAA2; MCOPS2
Applications