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Rabbit anti-BCoR Antibody
Bethyl Laboratories®
Catalog #
Target:
BCoR
Applications:
IP
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
between 25 and 75
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)
10 µl (1000 µg/ml)
Product Details
Specifications
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Additional Product Information
The BCL6 co-repressor (BCOR) was identified in a two-hybrid screen for factors that interact with the POZ domain of BCL6, a transcriptional repressor important to the immune response and B-cell development. BCOR also interacts with class I and II histone deacetylases and has recently been identified in a complexes with polycomb group proteins, RING1, RYBP, SNSC1, and RNF2, and the ubiquitin E3 ligase SKP1, and JHDM1B. Defects in BCOR are associated with oculo-facio-cardio-dental (OFCD) syndrome, a rare X-linked dominant disease that is fatal in males.
Alternate Names
