Rabbit anti-BAD IHC Antibody Affinity Purified
Catalog #
BAD
Human
,Mouse
IHC
,IHC-IF
Rabbit
Polyclonal
Whole IgG
Between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Cat,
Dog,
Monkey,
Rat
Human
2 - 8 °C
1 year from date of receipt
Antibody was affinity purified using an epitope specific to BAD immobilized on solid support.
The epitope recognized by IHC-00677 maps to a region between residue 1 and 50 of human BCL2-antagonist of cell death using the numbering given in entry NP_004313.1 (GeneID 572).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to BAD immobilized on solid support.
The epitope recognized by IHC-00677-T maps to a region between residue 1 and 50 of human BCL2-antagonist of cell death using the numbering given in entry NP_004313.1 (GeneID 572).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
BAD (Bcl2 agonist of cell death) is a member of the Bcl-2 family. Bcl-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with Bcl-xL and Bcl-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein [taken from NCBI Entrez Gene (GeneID:572)].
Alternate Names
BAD; BBC2; bcl2 antagonist of cell death; BCL2-antagonist of cell death protein; bcl2-associated agonist of cell death; bcl-2-binding component 6; BCL2-binding component 6; BCL2-binding protein; BCL2L8; bcl2-L-8; bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter
Applications