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Rabbit anti-ACINUS/ACN1 IHC Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

ACINUS/ACN1

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 1291 and C-term

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Guinea_pig,

Mouse,

Horse,

Dog,

Pig,

Rabbit,

X_laevis,

X_tropicalis,

Bovine,

Monkey,

Rat

Antigen Species

Human

Concentration
250 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

Acinus (Apoptotic Chromatin Condensation Inducer of the Nucleus) has been demonstrated to play a dual role in apoptosis and mRNA splicing. A proteolytic fragment of acinus generated by caspase cleavage appears to mediate chromatin condensation and DNA fragmentation. Acinus is also part of the ASAP (apoptosis and splicing-associated protein) complex that is deposited at exon-exon junctions during RNA splicing. In this complex acinus may be involved in pre-mRNA splicing.

22985

ACIN1

apoptotic chromatin condensation inducer 1

Q9UKV3

Apoptotic chromatin condensation inducer in the nucleus

Alternate Names

ACINUS; ACN; apoptotic chromatin condensation inducer in the nucleus; fSAP152; functional spliceosome-associated protein 152

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.