Rabbit anti-AAK1 Antibody Affinity Purified
Catalog #
AAK1
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 350 and 410
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Pig,
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
AAK1 (AP2-associated kinase 1) is a Ser/Thr protein kinase. The rat homolog was first identified in a screen of a rat brain cDNA library using a domain of the alpha subunit of the heterotetrameric AP2 complex as bait. The AP2 complex is one of two major coat proteins of endocytic vesicles that function in receptor-mediated endocytosis and the recycling of synaptic vesicles. AAK1 is responsible for phosphorylating the mu subunit of AP2 to promote clathrin-mediated endocytosis.
Alternate Names
adaptor-associated kinase 1; AP2-associated protein kinase 1
Applications