Rabbit anti-Phospho ERK1/2 (T202/Y204, T185/Y187) Antibody
Catalog #
ERK1/2 Phospho (T202/Y204 T185/Y187)
Human
WB
Rabbit
Polyclonal
Whole IgG
surrounding threonine 185 and tyrosine 187
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
X_laevis,
Bovine,
Rat,
D_melanogaster
Human
2 - 8 °C
1 year from date of receipt
Extracellular signal-regulated kinase 2 (ERK2/p42) is also known as mitogen-activated protein kinase 1 (MAPK1). ERK2 is part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK2 is very similar in sequence to ERK1/p44 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles.
Alternate Names
ERK; ERK2; ERK-2; ERT1; extracellular signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; MAPK 1; MAPK 2; MAPK2; mitogen-activated protein kinase 1; mitogen-activated protein kinase 2; p38; p40; p41; p41mapk; P42MAPK; p42-MAPK; PRKM1; PRKM2; protein tyrosine kinase ERK2
Applications