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Primary Antibodies  

Rabbit anti-Cyclin C IHC Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

Cyclin C

Reactivity:

Human

Applications:

IHC

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 244 and 294

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Guinea Pig,

Mouse,

Horse,

Zebra Finch,

Turkey,

Dog,

Chicken,

Pig,

Rabbit,

Bovine,

Monkey,

Rat

Antigen Species

Human

Concentration
100 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

Cyclin C is a member of the cyclin family of regulatory proteins that associate with and activate cyclin-dependent kinases (CDKs) to regulate cell cycle progression. Cyclins exhibit periodicity in their expression and activity which is regulated transcriptionally and post-transcriptionally via phosphorylation and ubiquitination. Cyclin C associates with cyclin-dependent kinase 8 (CDK8). It is also a component of the Mediator complex, a coactivator complex that provides a scaffold to link gene-specific transcription factors to RNA polymerase II and the general transcription machinery.

892

CCNC

cyclin C

P24863

Cyclin-C

Alternate Names

CycC; cyclin-C; hSRB11; SRB11; SRB11 homolog

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer or tris-EDTA pH9.0 buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.