/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-UVRAG IHC Antibody
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Primary Antibodies  

Rabbit anti-UVRAG IHC Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

UVRAG

Reactivity:

Human

,

Mouse

Applications:

IHC

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 649 and 699

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Presumed Reactivity

Guinea Pig,

Horse,

Pig,

Rabbit,

Bovine,

Rat

Antigen Species

Human

Concentration
250 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

UV radiation resistance associated gene (UVRAG) was first identified as a gene that could complement UV sensitivity in xeroderma pigmentosum cells. UVRAG may have tumor suppressor activity as mutations in the UVRAG gene have been associated with various human colon cancer cells and tissues. UVRAG has been shown to interact with Beclin 1 (Bcl-2-interacting protein), a protein that forms a complex with class III PI-3-kinase (PI3KC3) and is involved in autophagy. In this complex, UVRAG is proposed to function as a positive regulator of autophagy and a negative regulator of the growth of tumor cells.

7405

UVRAG

UV radiation resistance associated

Q9P2Y5

UV radiation resistance-associated gene protein

Alternate Names

beclin 1 binding protein; DHTX; disrupted in heterotaxy; p63; UV radiation resistance-associated gene protein; VPS38

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer or tris-EDTA pH9.0 buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.