NEW!
Bethyl Laboratories® Rabbit anti-DTL/CDT2 IHC Antibody, Affinity Purified - 100 µl (50+ slides)
Bethyl Laboratories
Catalog #
Validated
Target:
DTL/CDT2
Reactivity:
Human
,Mouse
Applications:
IHC
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 680 and C-terminus
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)
10 µl (5+ slides)
Product Details
Specifications
Verified Reactivity
Mouse,
Human
Presumed Reactivity
Monkey
Antigen Species
Human
Concentration
200 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Additional Product Information
DTL/CDT2 is a component of the CUL4A-DDB1 E3 ubiquitinating complex and plays a role in downregulating CDT1, an essential component of pre-replication complexes (Pre-RC) that ensures the genome is replicated only once per cycle. As part of the CUL4A-DDB1 E3 ligase complex DTL/CDT2 is also involved in the regulation of other proteins involved in the G2/M cell cycle checkpoint.
Alternate Names
CDT2; DCAF2; DDB1- and CUL4-associated factor 2; denticleless protein homolog; L2DTL; lethal(2) denticleless protein homolog; RAMP; RA-regulated nuclear matrix-associated protein; retinoic acid-regulated nuclear matrix-associated protein
Applications
