Rabbit anti-SF3a120/SAP114 IHC Antibody
Catalog #
SF3a120/SAP114
Human
,Mouse
IHC
,IHC-IF
Rabbit
Polyclonal
Whole IgG
Between 300 and 350
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Horse,
Dog,
Rabbit,
Bovine,
Monkey
Human
2 - 8 °C
1 year from date of receipt
SF3a120/SAP114 is a 120 kDa subunit of the heterotrimeric splicing factor 3a (SF3A) protein complex. SF3A along with SF3B and a 12S RNA subunit are components of the 17S U2 small nuclear ribonucleoprotein complex (U2 snRNP) involved in pre-mRNA splicing. SF3a120/SAP114 bears two SURP motif repeats and one ubiquitin-like domain. SURP motifs are found among proteins involved in regulated mRNA splicing. The SURP motifs along with the ubiquitin-like domain of SF3a120/SAP114 appear to function in the heterotrimeric formation between the 120, 60 and 66 kDa subunits.
Alternate Names
pre-mRNA processing 21; pre-mRNA splicing factor SF3a (120 kDa subunit); PRP21; PRPF21; SAP 114; SAP114; SF3A120; spliceosome-associated protein 114; splicing factor 3 subunit 1; splicing factor 3A subunit 1; splicing factor 3a, subunit 1, 120kD; splicing factor 3a, subunit 1, 120kDa
Applications
