Rabbit anti-IDH3B Antibody Affinity Purified
Catalog #
IDH3B
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 75 and 125
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Bovine
Human
2 - 8 °C
1 year from date of receipt
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit.Isocitric dehydrogenase subunit beta (IDH3B) is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase [taken from NCBI Entrez Gene (Gene ID: 3420)].
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
Alternate Names
isocitrate dehydrogenase NAD subunit beta, mitochondrial; isocitrate dehydrogenase 3 (NAD+) beta; isocitric dehydrogenase subunit beta; NAD(+)-specific ICDH subunit beta; RP46
Applications