Rabbit anti-DOCK2 Antibody Affinity Purified
Catalog #
DOCK2
Human
IP
Rabbit
Polyclonal
Whole IgG
Between 550 and 600
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Dedicator of cytokinesis protein 2 (DOCK2) is Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. DOCK2 activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. DOCK2 may also participate in IL2 transcriptional activation via the activation of RAC2 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q92608].
Alternate Names
dedicator of cyto-kinesis 2; dedicator of cytokinesis protein 2; IMD40
Applications