Rabbit anti-VAC14 Antibody Affinity Purified
Catalog #
VAC14
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 732 and 782
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]) [taken from NCBI Entrez Gene (Gene ID: 55697)].
Alternate Names
ArPIKfyve; protein VAC14 homolog; Tax1 (human T-cell leukemia virus type I) binding protein; Tax1-binding protein 2; TAX1BP2; TRX
Applications