Rabbit anti-LIN54 Antibody Affinity Purified
Catalog #
LIN54
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
LIN54 is a component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, LIN54 acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6MZP7].
Alternate Names
CXC domain-containing protein 1; CXCDC1; JC8.6; lin-54 homolog; MIP120; protein lin-54 homolog; TCX1
Applications