Rabbit anti-Beta-Arrestin 1 Antibody Affinity Purified
Catalog #
Beta-Arrestin 1
Human
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 368 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Beta-arrestin 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions [taken from NCBI Entrez Gene (Gene ID: 408)].
Alternate Names
ARB1; ARR1; arrestin 2; Arrestin beta-1; beta-arrestin-1; non-visual arrestin-2
Applications