/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-CENP-I Antibody
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Primary Antibodies  

Rabbit anti-CENP-I Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Citations (1)
Target:

CENP-I

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 50 and 100

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

Centromere protein I (CENP-I) is a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. CENP-I may be involved in incorporation of newly synthesized CENP-A into centromeres via its interaction with the CENPA-NAC complex. CENP-I is required for the localization of CENP-F, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. CENP-A is involved in the response of gonadal tissues to follicle-stimulating hormone [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q92674].

2491

CENPI

centromere protein I

Q92674

Centromere protein I

Alternate Names

CENP-I; centromere protein I; follicle-stimulating hormone primary response protein; FSH primary response 1; FSH primary response protein 1; FSHPRH1; interphase centromere complex protein 19; leucine-rich primary response protein 1; LRPR1

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.