Rabbit anti-ZC3H8 Antibody Affinity Purified
Catalog #
ZC3H8
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 50 and 100
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Zinc-finger CCCH domain-containing protein 8 (ZC3H8) acts as a transcriptional repressor of the GATA3 promoter. It is a sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (by similarity). ZC3H8 induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q8N5P1].
Alternate Names
Fliz1; ZC3HDC8; zinc finger CCCH domain-containing protein 8; zinc finger CCCH-type domain containing 8
Applications