/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-TRPC6 Antibody
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Primary Antibodies  

Rabbit anti-TRPC6 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

TRPC6

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 350 and 400

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

TRPC6 (transient receptor potential cation channel, subfamily C, member 6) forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in the TRPC6 gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2) [taken from NCBI Entrez Gene (Gene ID: 7225].

7225

TRPC6

transient receptor potential cation channel subfamily C member 6

Q9Y210

Short transient receptor potential channel 6

Alternate Names

focal segmental glomerulosclerosis 2; FSGS2; short transient receptor potential channel 6; transient receptor protein 6; TRP6; TRP-6; TrpC6

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.