NEW!
Rabbit anti-KLHL12 Antibody Affinity Purified
Bethyl Laboratories
Catalog #
Validated
Target:
KLHL12
Reactivity:
Human
Applications:
IP
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 150 and 200
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)
10 µl (1000 µg/ml)
Product Details
Specifications
Verified Reactivity
Human
Presumed Reactivity
Mouse,
Bovine,
Rat
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Additional Product Information
Kelch-like protein 12 (KLHL12) serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. KLHL12 negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q53G59].
Alternate Names
C3IP1; CUL3-interacting protein 1; DKIR; DKIR homolog; hDKIR; kelch-like protein 12; kelch-like protein C3IP1
Applications