/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-Ymer Antibody
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Primary Antibodies  

Rabbit anti-Ymer Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

Ymer

Reactivity:

Human

Applications:

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 1 and 50

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

Ymer was identified in a mass spectrometric study of epidermal growth factor signaling. It is a cytoplasmic tyrosine-phosphorylated protein that bears multiple ubiquitin-interacting domains. Recently Ymer has been implicated as a negative regulator of the NF-kappaB signaling pathway. Mutations in the gene that encodes Ymer, CCDC50, are the cause of autosomal dominant non-syndromic sensorineural deafness type 44.

152137

CCDC50

coiled-coil domain containing 50

Q8IVM0

Coiled-coil domain-containing protein 50

Alternate Names

C3orf6; coiled-coil domain-containing protein 50; DFNA44; protein Ymer; YMER

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.