/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-Par4 Antibody
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Primary Antibodies  

Rabbit anti-Par4 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

Par4

Reactivity:

Human

Applications:

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 290 and 340

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Mouse,

Rat

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

Par4 (prostate apoptosis response-4) was identified in a differential screen for pro-apoptotic genes in a prostate carcinoma cell line. Par4 activates apoptosis via the Fas prodeath pathway and by inhibition of NF-kappa-B transcriptional activity. Par4 may be a tumor suppressor. It has been shown to interact with a wide variety of proteins including atypical PKCs, and the Wilms’ tumor suppressor.

5074

PAWR

pro-apoptotic WT1 regulator

Q96IZ0

PRKC apoptosis WT1 regulator protein

Alternate Names

PAR4; Par-4; PRKC apoptosis WT1 regulator protein; PRKC, apoptosis, WT1, regulator; Prostate apoptosis response 4 protein; prostate apoptosis response protein 4; prostate apoptosis response protein PAR-4; prostate apoptosis response-4; transcriptional repressor PAR4; WT1-interacting protein

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.