Rabbit anti-CPSF160 Antibody Affinity Purified
Catalog #
CPSF160
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 1393 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
2 - 8 °C
1 year from date of receipt
Antibody was affinity purified using an epitope specific to CPSF160 immobilized on solid support.
The epitope recognized by A301-580A maps to a region between residue 1392 and 1442 of human cleavage and polyadenylation specific factor 1, 160kD subunit using the numbering given in entry NP_037423.1 (GeneID 29894).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to CPSF160 immobilized on solid support.
The epitope recognized by A301-580A-T maps to a region between residue 1392 and 1442 of human cleavage and polyadenylation specific factor 1, 160kD subunit using the numbering given in entry NP_037423.1 (GeneID 29894).
CPSF160/CPSF1 (cleavage and polyadenylation specific factor 1, 160 kDa subunit) is a subunit of the cleavage and polyadenylation specificity factor (CPSF) involved in mammalian mRNA 3’-end processing. CPSF, along with CstF (cleavage and stimulation factor), is critical for the recognition of cis-acting sequence elements on the pre-mRNA that dictate the site of cleavage and subsequent polyadenylation. CPSF exists as a complex of four proteins that includes CPSF160, CPSF100, CPSF73, and CPSF30. CPSF160 is responsible for recognizing the (AAUAAA) poly (A) signal for cleavage and polyadenylation.
Cleavage and polyadenylation specificity factor subunit 1
Alternate Names
cleavage and polyadenylation specific factor 1, 160kDa; cleavage and polyadenylation specificity factor 160 kDa subunit; cleavage and polyadenylation specificity factor subunit 1; CPSF 160 kDa subunit; CPSF160; HSU37012; P/cl.18; polyadenylation specificity factor
Applications