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Primary Antibodies  

Rabbit anti-PABP4 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Citations (7)
Target:

PABP4

Reactivity:

Human

,

Mouse

Applications:

IHC

,

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 525 and 575

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

PABP4 (poly(A)-binding protein 4), also known as iPABP (inducible poly(A)-binding protein) was originally identified in a search for activation-induced genes in T-cells. It is one of five poly(A)-binding proteins encoded by independent genes whose products play roles in various aspects of mRNA processing. The PABP genes encode one nuclear and four cytoplasmic PABP proteins. PABP2/PABP (PABPN1) is the observed nuclear PABP. The cytoplasmic PABPs include PABP1 (PABPC1), PABP3 (PABPC3), PABP4/iPABP (PABPC4), and x-linked PABP5 (PABPC5). The cytoplasmic PABPs bear four RNA-recognition motifs (RRMs) that participate in binding poly (A). In T-cells, PABP4 is proposed to play a role in stabilizing labile mRNA.

8761

PABPC4

poly(A) binding protein cytoplasmic 4

Q13310

Polyadenylate-binding protein 4

Alternate Names

activated-platelet protein 1; APP1; APP-1; inducible poly(A)-binding protein; iPABP; PABP4; PABP-4; poly(A) binding protein, cytoplasmic 4 (inducible form); poly(A)-binding protein 4; polyadenylate-binding protein 4

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.