/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-USP20/VDU2 Antibody
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Primary Antibodies  

Rabbit anti-USP20/VDU2 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Citations (13)
Target:

USP20/VDU2

Reactivity:

Human

,

Mouse

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 863 and 913

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific peptidase 20 (USP20) is a UBP and is also called von-Hippel-Lindau protein (pVHL) interacting deubiquitinating enzyme 2 (VDU2). pVHL is an E3 ubiquitin-ligase that ubiquitinates hypoxia-inducible factor (HIF)-1alpha. USP20/VDU2 functions to specifically deubiquitinate HIF-1alpha to increase expression of HIF-1alpha regulated genes.

10868

USP20

ubiquitin specific peptidase 20

Q9Y2K6

Ubiquitin carboxyl-terminal hydrolase 20

Alternate Names

deubiquitinating enzyme 20; hVDU2; LSFR3A; pVHL-interacting deubiquitinating enzyme 2; ubiquitin carboxyl-terminal hydrolase 20; ubiquitin thioesterase 20; ubiquitin thiolesterase 20; ubiquitin-specific-processing protease 20; VDU2; VHL-interacting deubiquitinating enzyme 2

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.