Rabbit anti-LIS-1 Antibody
Catalog #
LIS-1
Human
,Mouse
,Rat
WB
Rabbit
Polyclonal
Whole IgG
between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Rat,
Mouse,
Human
Cat,
Chicken,
Pig,
X_laevis,
X_tropicalis,
Zebrafish,
Bovine
Human
2 - 8 °C
1 year from date of receipt
Lissencephaly-1 protein (LIS-1) was identified as a gene associated with Miller-Dieker lissencephaly syndrome, an autosomal dominant disorder characterized by microcephaly along with anomalies of the kidney, heart, and gastrointestinal tract. LIS-1 is the non-catalytic alpha subunit of the intracellular isoform of platelet-activating factor acetylhydrolase. LIS-1 plays an important role in neuron migration during brain development and fibroblast migration during wound healing. Its role in migration is related to its function in regulating dynein-mediated microtubule sliding.
Platelet-activating factor acetylhydrolase IB subunit alpha
Alternate Names
LIS1; LIS-1; LIS2; lissencephaly 1 protein; Lissencephaly-1 protein; MDCR; MDS; NudF; PAF acetylhydrolase 45 kDa subunit; PAFAH; PAF-AH 45 kDa subunit; PAFAH alpha; PAF-AH alpha; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa); platelet-activating factor acetylhydrolase IB subunit alpha; platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD); platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)
Applications