XPF/ERCC4 Antibody

XPF/ERCC4 is suggested to play a role in the repair of DNA double-strand breaks (DSB), homologous recombination, and gene conversion via single-strand annealing (SSA). XPF/ERCC4 is an endonuclease that incises 5-prime DNA. Defects in XPF/ERCC4 cause xeroderma pigmentosum VI (XP6) an autosomal recessive disease characterized by hypersensitivity to sunlight and a predisposition to skin cancer as well as neurological abnormalities. Defects in XPF/ERCC4 are also responsible for XFE progeroid syndrome, a syndrome characterized by dwarfism, cachexia, and microcephaly.
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit
DNA repair endonuclease XPF
:  DNA excision repair protein ERCC-4 DNA repair protein complementing XP-F cells ERCC11 excision repair cross-complementation group 4 excision repair cross-complementing rodent repair deficiency, complementation group 4 excision-repair, complementing defective, in Chinese hamster FANCQ RAD1 xeroderma pigmentosum group F-complementing protein xeroderma pigmentosum, complementation group F XFEPS XPF More... Less...
Product
Specifications
Ordering Information
Human
WB, IP, IHC-P
Between 855 and 905
$339
$229
$99
Human
IHC-P
Between 855 and 905
$360
$99