UBQLN4/CIP75/Ubiquilin 4 Antibody

Ubiquilin-4 (UBQLN4) plays a role in the regulation of protein degradation via the ubiquitin-proteasome system (UPS). It mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. UBQLN4 Plays a role in the regulation of the proteasomal degradation of non-ubiquitinated GJA1 (By similarity). It acts as an adapter protein that recruits UBQLN1 to the autophagy machinery and mediates the association of UBQLN1 with autophagosomes and the autophagy-related protein LC3 (MAP1LC3A/B/C) and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (PubMed:23459205) [taken from NCBI Entrez Gene (Gene ID: 56893)].
UBQLN4
ubiquilin 4
Ubiquilin-4
:  A1U A1Up ataxin-1 interacting ubiquitin-like protein ataxin-1 ubiquitin-like interacting protein ataxin-1 ubiquitin-like-interacting protein A1U C1orf6 chromosome 1 open reading frame 6 CIP75 connexin43-interacting protein of 75 kDa UBIN
Product
Specifications
Ordering Information
Human
WB, IP
between 1 and 50
$339
$229
$99