SPF45 Antibody

Splicing factor 45 (SPF45) is an RNA splicing factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. SPF45 is involved in the regulation of alternative splicing and the utilization of cryptic splice sites. It has been shown to promote the utilization of a cryptic splice site created by the beta-110 mutation in the human beta-thalassemia gene. The resulting frameshift leads to sickle cell anemia [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96125].
RBM17
RNA binding motif protein 17
Splicing factor 45
:  45 kDa-splicing factor MGC14439 RNA-binding motif protein 17 SPF45 splicing factor 45kDa
Product
Specifications
Ordering Information
Human
IP, IHC-P
Between 25 and 75
100
$339
$99
Human
WB, IP, IHC-P
Between 351 and 401
100
$339
$229
$99
Human
100
Includes: 1 each of A302-497A and A302-498A
$472
Includes: 1 each of A302-497A and A302-498A
Human, Mouse
IHC-P
Between 25 and 75
100
$360
$99