SMN1 Antibody

Survival motor neuron protein (SMN1) has been identified as the gene that is defective in spinal muscular atrophy (SMA), a neurodegenerative autosomal recessive disease characterized by paralysis and muscular atrophy which results from the loss of motor neurons in the spinal cord. There are two closely related SMN genes that do not appear to be functionally redundant. SMN1 represents the telomeric copy while SMN2 represents the centromeric copy. In the cell, SMN1 is part of a large complex of proteins involved in snRNP biogenesis. The functional role of SMN1 is proposed to play a role in messenger and ribosomal RNA transcription and processing.
SMN1
survival of motor neuron 1, telomeric
Survival motor neuron protein
:  BCD541 component of gems 1 GEMIN1 gemin-1 SMA SMA@ SMA1 SMA2 SMA3 SMA4 SMN SMNT spinal muscular atrophy (Werdnig-Hoffmann disease, Kugelberg-Welander disease) survival motor neuron 1 protein T-BCD541 TDRD16A tudor domain containing 16A
Product
Specifications
Ordering Information
Human
IP
Between 50 and 100
$339
$99
Human
WB, IP, PLA
Between 244 and 294
$339
$229
$99
Human
Includes: 1 each of A301-862A and A301-863A
$472
Includes: 1 each of A301-862A and A301-863A