Solute carrier family 46 member 1 (SLC46A1) has been shown to act both as an intestinal proton-coupled high-affinity folate transporter and as an intestinal heme transporter which mediates heme uptake from the gut lumen into duodenal epithelial cells. The iron is then released from heme and may be transported into the bloodstream. Dietary heme iron is an important nutritional source of iron. SLC46A1 shows a higher affinity for folate than heme [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96NT5].
heme carrier protein 1•
proton-coupled folate transporter•
solute carrier family 46 (folate transporter), member 1•
Solute carrier family 46 member 1•
solute carrier family 46, member 1•