Liprin beta 1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. Liprin beta 1 was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiments demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2 [taken from NCBI Entrez Gene (Gene ID: 8496)].
liprin beta 1•
liprin related protein•
protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1•
protein-tyrosine phosphatase receptor-type f polypeptide-interacting protein-binding protein 1•
PTPRF interacting protein, binding protein 1 (liprin beta 1)•
PTPRF-interacting protein-binding protein 1•