FBW7 Antibody

FBW7 (F-box and WD repeat domain containing 7) is a member of the F-box family of proteins. The F-box is a protein-protein interaction motif first identified in cyclin F. F-box proteins associate with SCFs (Skp1-cullin-F-box protein ligase complexes) which are E3 ligases that ubiquitinate proteins and target them for proteasomal degradation. FBW7 has been found to bind and specifically target cyclin E and the Notch intracellular domain (NICD) for ubiquitination. Defects in FBW7 may contribute to tumorigenesis.
FBXW7
F-box and WD repeat domain containing 7
F-box/WD repeat-containing protein 7
:  AGO archipelago Archipelago homolog archipelago homolog (Drosophila) CDC4 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila) F-box and WD-40 domain-containing protein 7 F-box protein FBW7 F-box protein FBX30 F-box protein SEL-10 FBW6 FBW7 FBX30 FBXO30 FBXW6 FLJ11071 hAgo hCdc4 homolog of C elegans sel-10 SEL10 SEL-10 More... Less...
Product
Specifications
Ordering Information
Human
IP
Between 1 and 50
$339
$99
Human
IP, IHC-P
Between 50 and 100
$339
$99
Human
Includes: 1 each of A301-720A and A301-721A
$472
Includes: 1 each of A301-720A and A301-721A
Human
IHC-P
Between 50 and 100
$360
$99