STAT2 Antibody

Signal transducer and activator of transcription 2 (STAT2) is a signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P52630].
STAT2
signal transducer and activator of transcription 2
Signal transducer and activator of transcription 2
:  IMD44 interferon alpha induced transcriptional activator ISGF-3 P113 signal transducer and activator of transcription 2, 113kD signal transducer and activator of transcription 2, 113kDa STAT113
Product
Specifications
Ordering Information
Human
IP, IHC-P
Between 175 and 225
100
$339
$99
Human
WB, IP, IHC-P
Between 725 and 775
100
$339
$229
$99
Human
WB, IP, IHC-P
Between 801 and 851
100
$339
$229
$99
Human
100
Includes: 1 each of A303-510A, A303-511A and A303-512A
$707
Includes: 1 each of A303-510A, A303-511A and A303-512A