CRM1 Antibody

Chromosome region maintenance 1 protein homolog (CRM1) is the Ran-GTP-binding nuclear export receptor for proteins bearing a leucine rich nuclear export signal and RNAs. CRM1 also possesses a mitotic function as it localizes to kinetochores, and with Ran-GTP, recruits Ran-GTPase-activating protein (Ran-GAP1) and Ran-binding protein (Ran-BP2) for proper mitotic spindle assembly and chromosome segregation. Additionally, CRM1 is suggested to function as a loading dock of various cell cycle and checkpoint factors such as cyclins, Cdks, p53 and BRCA1, to regulate proper chromosome duplication and genomic stability.
XPO1
exportin 1
Exportin-1
:  chromosome region maintenance 1 homolog chromosome region maintenance 1 homolog (yeast) chromosome region maintenance 1 protein homolog CRM1 emb exp1 exportin 1 (CRM1 homolog, yeast) exportin 1 (CRM1, yeast, homolog) exportin-1 (required for chromosome region maintenance) More... Less...
Product
Specifications
Ordering Information
Human, Mouse
WB, IP, IHC-P, PLA
Between 1025 and C-term
$339
$229
$99
Human
IP
Between 375 and 425
$339
$99
Human, Mouse
Includes: 1 each of A300-469A and A300-490A
$472
Includes: 1 each of A300-469A and A300-490A
Human, Mouse
IHC-P
Between 1025 and C-term
$360
$99