CCDC88A Antibody

CCDC88A encodes the protein known as GIV (G alpha-interacting vesicle-associated protein) and Girdin. CCDC88A plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. CCDC88A Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. CCDC88A has also been found to be essential for the integrity of the actin cytoskeleton and for cell migration. It is required for formation of actin stress fibers and lamellipodia, and it may be involved in membrane sorting in the early endosome [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q3V6T2].
CCDC88A
coiled-coil domain containing 88A
Girdin
:  Akt phosphorylation enhancer Akt-phosphorylation enhancer APE Coiled-coil domain-containing protein 88A FLJ10392 g alpha-interacting vesicle-associated protein Galpha-interacting vesicle-associated protein girders of actin filament girders of actin filaments girdin GIV GRDN HkRP1 Hook-related protein 1 KIAA1212 More... Less...
Product
Specifications
Ordering Information
Human
IP
Between 425 and 475
100
$339
$99
Human
WB, IP
Between 1425 and 1475
100
$339
$229
$99
Human
100
Includes: 1 each of A303-101A and A303-102A
$472
Includes: 1 each of A303-101A and A303-102A