ROCK2 Antibody

Rho-associated protein kinase 2 (ROCK2), or Rho kinase alpha, is a serine-threonine protein kinase that plays an important role in cellular apoptosis, growth, cell motility and cell contraction. ROCK2 shares an overall 65% homology in amino acid sequence with ROCK1. The ROCK1 and ROCK2 isoforms are products of two separate genes. Both ROCK1 and ROCK2 are downstream targets of the Rho A small GTP-binding protein. As downstream effectors of RhoA, ROCK1 and ROCK2 mediate changes in the actin cytoskeleton via phosphorylation of target proteins such as the MBS subunit of MLCP, MLC, ERM proteins, protein LIM kinase and adducin.
ROCK2
Rho associated coiled-coil containing protein kinase 2
Rho-associated protein kinase 2
:  p164 ROCK-2 Rho kinase 2 Rho-associated, coiled-coil-containing protein kinase 2 rho-associated, coiled-coil-containing protein kinase II ROCK-II
Product
Specifications
Ordering Information
Human
WB, IP
Between 1 and 100
100
$339
$229
$99
Human
WB, IP, PLA
Between 1320 and C-term
100
$339
$229
$99
Human
100
Includes: 1 each of A300-046A and A300-047A
$472
Includes: 1 each of A300-046A and A300-047A