MKK4 Antibody

MAPKK4 (mitogen-activated protein kinase kinase 4) is a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. MAPKK4 is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. Studies in knockout mice suggest that MAPKK4 mediates survival signals in T cell development. It may also be important to liver organogenesis.[taken from NCBI Entrez Gene (GeneID: 6416)].
MAP2K4
mitogen-activated protein kinase kinase 4
Dual specificity mitogen-activated protein kinase kinase 4
:  c-Jun N-terminal kinase kinase 1 JNK-activated kinase 1 JNK-activating kinase 1 JNKK JNKK1 MAP kinase kinase 4 MAPK/ERK kinase 4 MAPKK 4 MAPKK4 MEK 4 MEK4 MKK4 PRKMK4 SAPK kinase 1 SAPK/ERK kinase 1 SAPKK1 SAPKK-1 SEK1 SERK1 SKK1 stress-activated protein kinase kinase 1
Product
Specifications
Ordering Information
Human
IP
Between 50 and 100
$339
$99
Human, Mouse
WB, IP
Between 349 and 399
$339
$229
$99
Human, Mouse
Includes: 1 each of A302-657A and A302-658A
$472
Includes: 1 each of A302-657A and A302-658A