UBR1 Antibody

UBR1 is an E3 ubiquitin-protein ligase that is a component of the N-end rule pathway. UBR1 recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. UBR1 may be involved in pancreatic homeostasis. UBR1 binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q8IWV7].
UBR1
ubiquitin protein ligase E3 component n-recognin 1
E3 ubiquitin-protein ligase UBR1
:  E3a ligase JBS N-recognin-1 ubiquitin ligase E3 alpha-I ubiquitin-protein ligase E3-alpha ubiquitin-protein ligase E3-alpha-1 ubiquitin-protein ligase E3-alpha-I
Product
Specifications
Ordering Information
Human
IP
Between 225 and 275
$339
$99
Human
WB, IP
Between 1125 and 1175
$339
$229
$99
Human
Includes: 1 each of A302-987A and A302-988A
$472
Includes: 1 each of A302-987A and A302-988A