Rabbit anti-PDK1 Antibody
Catalog #
PDK1
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 506 and 556
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human,
Mouse
Human
2 - 8 °C
1 year from date of receipt
PDK1 (3-phosphoinositide-dependent kinase-1) is a serine/threonine kinase that contains a PH domain for binding of phosphatidylinositols (PtdIns). PDK1 phosphorylates PKB/AKT in response to agonist stimulation of phosphoinositide 3-kinases (PI3Ks). Stimulation of PI3Ks generates specific inositol lipids that are important for activation of PDK1. PDK1 may also be responsible for phosphorylating PKA, PKC-zeta, RPS6KA1, and RPS6KB1.
3-phosphoinositide-dependent protein kinase 1
Alternate Names
3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; hPDK1; PDK1; PDPK2; PDPK2P; PkB kinase like gene 1; PRO0461
Applications